Apolipoprotein A-1

Alternate Name: Alpha-Apolipoprotein

  | APO a

SAL Code:

1004

CPT:

82172

Loinc:

1869-7

Turn Around Time:

1-2 days

Units:

mg/dL

Department:

Special Chemistry

Methodology:

Immunologic

Specimen Requirements:

Primary Tube:

SST

Primary Substance:

Serum

Alternate Sample Info:

Red-top tube, green-top (heparin) tube, or lavender-top (EDTA) tube

Temperature

Period

Stable Ambient:

14 Days

Stable Fridge:

14 days

Stable Frozen:

14 days

Rejection Criteria:

Improper labeling

Clinical Info:

Apo A-1 comprises 60% to 70% of the protein content of HDL. Apo A-1 serves as an activator of LCAT which is involved in the transport of cholesterol from peripheral tissues to the liver where it is degraded. Decreased serum HDL cholesterol levels have been reported to correlate with increased risk of coronary artery disease (CAD); however, Apo A-1 has been suggested as a better discrimination of CAD than HDL. Apo A-1 levels also correlate with survival rates or risk factors for patients with myocardial infarction and peripheral vascular disease. Measurement of Apo A-1 may also aid in the diagnosis of Tangier disease (absence of alpha-lipoprotein).

Sample Collection:

Patient must be fasting 12 to 14 hours. Collect patient samples using standard phlebotomy techniques. Click here for additional collection instructions.

Test Handle Instructions:

Maintain at room temperatrure.

Test Information:

Components: