Creatine Kinase (CK), Total

Alternate Name: CK

  | Creatine Phosphokinase, Total

SAL Code:

318

CPT:

82550

Loinc:

2157-6

Turn Around Time:

1 Day

Setup:

Daily

Units:

U/L

Department:

Chemistry

Specimen Requirements:

Primary Tube:

SST

Primary Substance:

Serum

Alternate Sample Info:

Red Top; Green Top (sodium heparin) tube.

Temperature

Period

Stable Ambient:

7 Days

Stable Fridge:

7 Days

Stable Frozen:

30 Days

Rejection Criteria:

Gross hemolysis; improper labeling

Clinical Info:

The CK test may be helpful to detect muscle damage in certain cases where a patient might be taking a drug such as a statin, using ethanol or cocaine, have experienced physical trauma; or might have been exposed to toxins that may cause muscle damage. CK can also be elevated in the hours following an acute myocardial infarction. If a CK is elevated and the location of the muscle damage is unclear, then a health practitioner may order CK isoenzymes (SAL# 353) as a follow-up test, to distinguish between the three types (isoenzymes) of CK: CK-MB (found primarily in heart muscle), CK-MM (found primarily in skeletal muscle), and CK-BB (found primarily in the brain; when present in the blood, it is primarily from smooth muscles, including those in intestines, uterus or placenta).

Additional Information:

Measurements of Creatine Kinase can be used in the diagnosis and treatment of muscle disease and myocardial infarction. Other conditions such as progressive Duchenne-type muscular dystrophy, or myxedema (hypothyroidism) can cause elevated levels of CK. This test can also be used to detect inflammation of muscles (myositis) or serious muscle damage and/or to diagnose rhabdomyolysis. Strenuous exercising, particularly where muscles may be torn or damaged may also cause elevated CK levels.

Sample Collection:

Collect patient samples using standard phlebotomy techniques. Click here for additional collection instructions.
Separate serum or plasma from cells within 45 minutes of collection.

Test Information:

Components: