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Cocaine

Alternate Name: COCAINE URINE

  | COCAINE DOA

SAL Code:

612

CPT:

80101

Loinc:

20519-5

Turn Around Time:

1 Day

Setup:

Daily

Units:

ng/mL

Department:

Drug Screen

Performing Laboratory:

Sherman Abrams Laboratory

Specimen Requirements:

Primary Tube:

Clean & Sterile Cup

Primary Substance:

Urine

Temperature

Period

Stable Ambient:

7 Days

Stable Fridge:

30 Days

Stable Frozen:

>30 Days

Rejection Criteria:

Urine samples that are not clear. Improper labeling, samples that are suspect for adulteration or dilution.

Clinical Info:

The assay results distinguish between positive and negative specimens:
- positive indicating specimens contain detectable cocaine metabolites;
- negative indicating specimens do not contain cocaine metabolites, or the cocaine metabolites are present in concentrations below the cutoff level for this assay.
-The cut-off level of detection for this assay is 300 ng/mL.

Additional Information:

Detect the presence of cocaine metabolites in urine. This is a screening test and will reflex to confirmatory testing where indicated.
Cocaine is almost completely metabolized, primarily in the liver, with only about one percent excreted in the urine unchange. Most cocaine is eliminated as benzoylecgonine, the major metabolite of cocaine. Cocaine is also excreted in relatively lesser amounts as ecgonine methyl ester and ecgonine. Cocaine metabolites may be detected in urine for up to several days after ingested.

Sample Collection:

Clean catch or catheterized urine in a clean and sterile container with no preservatives.

Test Limitations:

This cocaine assay is for screening purposes only. The test will reflex to a more specific method if the screening test is positive, and reflex is indicated.
1. The assay is designed for use only with human urine.
2. A positive result from the assay indicates the presence of cocaine or its metabolites but does not indicate or measure intoxication.
3. Other substances and/or factors not listed (e.g., technical or procedural errors) may interfere with the test and cause false results.
4. Interpretation of results must take into account that urine concentrations can vary extensively with fluid intake and other biological variables.
5. Immunoassays that produce a single result in the presence of a drug and its metabolites cannot fully quantitative the concentration of individual components.

Specimen Handling Instructions:

The urine should be collected in a clean, dry container. Urine collected at any time of day may be used. Urine specimens containing visible particles should be centrifuged, filtered, or allowed to settle to obtain a clear specimen for testing.

Test Information:

Components:

Brooklyn Navy Yard
Building 292, Suite 416
63 Flushing Avenue
Brooklyn, NY 11205

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