Cancer Antigen (CA) 15-3

Alternate Name: Ca15-3

SAL Code:

747

CPT:

86300

Loinc:

6875-9

Turn Around Time:

1 Day

Setup:

Daily

Units:

U/mL

Department:

Tumor Markers

Specimen Requirements:

Primary Tube:

SST

Primary Substance:

Serum

Temperature

Period

Stable Ambient:

7 Days

Stable Fridge:

7 Days

Stable Frozen:

28 Days

Clinical Info:

In general, the higher the CA 15-3 level, the more advanced the breast cancer and the larger the tumor burden. CA 15-3 concentrations tend to increase as the cancer grows. In metastatic breast cancer, the highest levels of CA 15-3 often are seen when the cancer has spread to the bones and/or the liver. Increasing concentrations of CA 15-3 over time may indicate that a person is not responding to treatment or that the cancer is recurring. Levels within the normal range do not preclude the presence of cancer, nor are elevated results an absolute indication of malignancy. CA 125 test results should be interpreted in conjunction with other clinical and laboratory findings.

Additional Information:

CA 15-3 may be ordered along with other tests, such as estrogen and progesterone receptors, Her2/neu, and gene expression tests for breast cancer, when advanced breast cancer is first diagnosed to help determine cancer characteristics and treatment options. If CA 15-3
is initially elevated, then it may be ordered periodically to monitor the effectiveness of treatment and to help watch for recurrence. CA 15-3 is usually not ordered
when breast cancer is detected early, before it has metastasized, because levels will not be elevated in the majority of early cancers.

Sample Collection:

Collect patient samples using standard phlebotomy techniques. Click here for additional collection instructions.

Test Information:

Components: